About the project:
We have engineered an in vitro 3-Dimensional (3D) cell culture integrated into a flow-cell bioreactor to conduct the toxicological assessment of environmental polyaromatic hydrocarbons (PAHs) mixtures that can be found in food. The proposed bioreactor system is already up and running and can mimic the intestinal tract, where nutrients and potential contaminants are absorbed by cells.
The experimental approach for this investigation will involve using human, mice, and pig intestinal cell lines (since both have high genomic similarity to humans) to be cultured inside the 3-dimensionally bioreactor to analyze toxicological markers and determine the toxicity of the mixture.
Background
We seek a postdoctoral researcher within the field of environmental sciences, toxicology, cell biology, or bioengineering to work on a multidisciplinary project involving the investigation of the toxicity of PAHs in intestinal cells. In this investigation, we are using OMICS tools but also human/mammalian cell cultures.
Duties and responsibilities
The postdoctoral researcher will be primarily in charge of the bioreactor cell culture growth and transcriptomics investigation. The postdoc should have experience in growing mammalian cells, and conduct toxicological experiments. Some bioinformatics knowledge would be beneficial as well. Opportunities to learn how to write proposals will also be available for students seeking to become faculty members in the future.
English proficiency is a requirement.
Information
The position is a position for a fixed term of one year, with the potential to extend for three years. The salary depends on the successful candidate’s qualifications and experience.
For more information, please contact Prof. Debora F. Rodrigues, dfrigirodrigues@uh.edu. The University of Houston actively pursues an equal work environment and values the qualities that diversity adds to our operations.
Application
Initial screening of applications will be made via email to Dr. Rodrigues.
For the application to be complete and considered, the following electronic documents must be included in a single PDF:
• A cover letter, outlining your overall experience in the field of the project
• CV with a relevant description of your overall qualifications and experience
• Name of 2 to 3 Professors that can serve as references for your application